Package: drugfindR 0.99.1017
drugfindR: Investigate iLINCS for candidate repurposable drugs
This package provides a convenient way to access the LINCS Signatures available in the iLINCS database. These signatures include Consensus Gene Knockdown Signatures, Gene Overexpression signatures and Chemical Perturbagen Signatures. It also provides a way to enter your own transcriptomic signatures and identify concordant and discordant signatures in the LINCS database.
Authors:
drugfindR_0.99.1017.tar.gz
drugfindR_0.99.1017.zip(r-4.5)drugfindR_0.99.1017.zip(r-4.4)
drugfindR_0.99.1017.tgz(r-4.4-any)
drugfindR_0.99.1017.tar.gz(r-4.5-noble)drugfindR_0.99.1017.tar.gz(r-4.4-noble)
drugfindR_0.99.1017.tgz(r-4.4-emscripten)
drugfindR.pdf |drugfindR.html✨
drugfindR/json (API)
NEWS
# Install 'drugfindR' in R: |
install.packages('drugfindR', repos = c('https://cogdisreslab.r-universe.dev', 'https://cloud.r-project.org')) |
Bug tracker:https://github.com/cogdisreslab/drugfindr/issues
lincsilincsdrug repurposingdrug discoverytranscriptomicsgene expressiongene knockdowngene overexpressionchemical perturbagendrugfindrbioinformaticsbioinformatics-pipeline
Last updated 3 days agofrom:36ddde52f6. Checks:OK: 5. Indexed: yes.
Target | Result | Date |
---|---|---|
Doc / Vignettes | OK | Dec 23 2024 |
R-4.5-win | OK | Dec 23 2024 |
R-4.5-linux | OK | Dec 23 2024 |
R-4.4-win | OK | Dec 23 2024 |
R-4.4-mac | OK | Dec 23 2024 |
Exports:consensusConcordantsfilterSignaturegetConcordantsgetSignatureinvestigateSignatureinvestigateTargetprepareSignature
Dependencies:askpassBiocGenericsbitbit64clicliprcpp11crayoncurldplyrfansigenericsgluehmshttr2lifecyclemagrittropensslpillarpkgconfigprettyunitsprogresspurrrR6rappdirsreadrrlangS4Vectorsstringistringrsystibbletidyselecttzdbutf8vctrsvroomwithr
Readme and manuals
Help Manual
Help page | Topics |
---|---|
Generate a Consensus list of Targets *[Stable]* | consensusConcordants |
Filter the L1000 Signature *[Stable]* | filterSignature |
Get Concordant Signatures from iLINCS *[Stable]* | getConcordants |
Get the L1000 Signature from iLINCS *[Stable]* | getSignature |
Investigate a given DGE dataset *[Stable]* | investigateSignature |
Investigate a Given Gene or Drug *[Stable]* | investigateTarget |
Prepare an L1000 Signature froma given differential gene expression output *[Stable]* | prepareSignature |
Rename the Target-Related Columns | targetRename |