Package: drugfindR
Title: Investigate iLINCS for candidate repurposable drugs
Version: 1.1.0
Authors@R: c(
    person(given = c("Ali", "Sajid"),
           family = "Imami",
           role = c("aut", "cre"),
           email = "Ali.Sajid.Imami@gmail.com",
           comment = c(ORCID = "0000-0003-3684-3539")),
    person(given = c("Smita"),
            family = "Sahay",
            role = c("aut"),
            email = "Smita.Sahay@rockets.utoledo.edu",
            comment = c(ORCID = "0009-0003-4377-8963")),
    person(given = c("Justin", "Fortune"),
           family = "Creeden",
           role = c("aut"),
           email = "Justin.Creeden@rockets.utoledo.edu",
           comment = c(ORCID = "0000-0003-3123-8401")),
    person(given = c("Robert", "Erne"),
          family = "McCullumsmith",
          role = c("ctb", "fnd"),
          email = "Robert.McCullumsmith@utoledo.edu",
          comment = c(ORCID = "0000-0001-6921-7150"))
    )
Description: This package provides a convenient way to access the LINCS
        Signatures available in the iLINCS database. These signatures
        include Consensus Gene Knockdown Signatures, Gene
        Overexpression signatures and Chemical Perturbagen Signatures.
        It also provides a way to enter your own transcriptomic
        signatures and identify concordant and discordant signatures in
        the LINCS database.
License: GPL-3 + file LICENSE
Encoding: UTF-8
URL: https://github.com/CogDisResLab/drugfindR,
        https://cogdisreslab.github.io/drugfindR/
BugReports: https://github.com/CogDisResLab/drugfindR/issues
Roxygen: list(markdown = TRUE)
RoxygenNote: 7.3.3
biocViews: FunctionalPrediction, DifferentialExpression,
        GeneSetEnrichment, SingleCell, Network
Imports: tibble, rlang, dplyr, purrr, readr, stringr, stats, lifecycle,
        S4Vectors, httr2, curl, DFplyr
Depends: R (>= 4.5.0)
Suggests: AnnotationDbi, BiocStyle, biocthis, codemetar, devtools,
        here, httptest2, jsonlite, knitr, rmarkdown, testthat (>=
        3.0.0), tidyverse, usethis
Config/testthat/edition: 3
Config/testthat/parallel: true
VignetteBuilder: knitr
X-schema.org-applicationCategory: Genomics
X-schema.org-keywords: LINCS, iLINCS, drug repurposing, drug discovery,
        transcriptomics, gene expression, gene knockdown, gene
        overexpression, chemical perturbagen, drugfindR
X-schema.org-isPartOf: https://bioconductor.org
Collate: 'utilities.R' 'consensusConcordants.R' 'drugfindR-package.R'
        'filterSignature.R' 'getConcordants.R' 'getSignature.R'
        'prepareSignature.R' 'investigateSignature.R'
        'investigateTarget.R'
Config/pak/sysreqs: libicu-dev libssl-dev libx11-dev
Repository: https://cogdisreslab.r-universe.dev
Date/Publication: 2026-06-24 10:08:12 UTC
RemoteUrl: https://github.com/CogDisResLab/drugfindR
RemoteRef: HEAD
RemoteSha: 93f378d37012133374de77daaead03ac52dcb6db
NeedsCompilation: no
Packaged: 2026-06-24 10:22:29 UTC; root
Author: Ali Sajid Imami [aut, cre] (ORCID:
    <https://orcid.org/0000-0003-3684-3539>),
  Smita Sahay [aut] (ORCID: <https://orcid.org/0009-0003-4377-8963>),
  Justin Fortune Creeden [aut] (ORCID:
    <https://orcid.org/0000-0003-3123-8401>),
  Robert Erne McCullumsmith [ctb, fnd] (ORCID:
    <https://orcid.org/0000-0001-6921-7150>)
Maintainer: Ali Sajid Imami <Ali.Sajid.Imami@gmail.com>