Package: KINNET Type: Package Title: Kinase INteraction NETwork Generation Version: 0.4.0.9002 Authors@R: c( person(given = c("Ali", "Sajid"), family = "Imami", role = c("aut", "cre"), email = "Ali.Sajid.Imami@gmail.com", comment = c(ORCID = "0000-0003-3684-3539")), person(given = "Khaled", family = "Alganem", role = c("aut"), email = "Khaled.Alganem@rockets.utoledo.edu", comment = c(ORCID = "0000-0003-3234-7669")), person(given = c("Justin", "Fortune"), family = "Creeden", role = c("aut"), email = "Justin.Creeden@rockets.utoledo.edu", comment = c(ORCID = "0000-0003-3123-8401")), person(given = "Alex", family = "Joyce", role = c("aut"), email = "Alex.Joyce2@rockets.utoledo.edu", comment = c(ORCID = "0000-0003-0303-2481"))) Description: This package provides the functionality to process PamGene's PamChip Data Output and generate kinase interaction networks from that. This project uses a bayesian algorithm to generate bayesian networks for defining dependence relationships between peptide sequences in the PamChip data. It then uses a novel kinase assignment method to assign upstream kinases to each peptide which is then output as a graph. License: GPL (>= 3) | file LICENSE Encoding: UTF-8 Imports: methods, readr, dplyr, tibble, bnlearn, stringr, tidyselect, purrr, tidyr, Rgraphviz, graph, rlang, effectsize Depends: R (>= 2.10) RoxygenNote: 7.1.1 Collate: 'assign_kinases.R' 'compare_kinased_graphs.R' 'distances.R' 'equalize_kinase_graphs.R' 'filter_peptides.R' 'make_model.R' 'pamchip_data.R' 'pamchip_data_ptk.R' 'pamchip_data_stk.R' 'probability_matrix.R' 'ptk_methods.R' 'render_kinased_graph.R' 'render_reduced_kinased_graph.R' 'stk_methods.R' 'subset_data.R' 'update_probability_matrix.R' Suggests: testthat (>= 3.0.0) Config/testthat/edition: 3 Repository: https://cogdisreslab.r-universe.dev Date/Publication: 2022-01-14 16:32:11 UTC RemoteUrl: https://github.com/CogDisResLab/KINNET RemoteRef: HEAD RemoteSha: 8c901f74fee88662aa6630dbe536ba08e7a7af54 NeedsCompilation: no Packaged: 2026-07-06 06:08:22 UTC; root Author: Ali Sajid Imami [aut, cre] (ORCID: ), Khaled Alganem [aut] (ORCID: ), Justin Fortune Creeden [aut] (ORCID: ), Alex Joyce [aut] (ORCID: ) Maintainer: Ali Sajid Imami